Taking one dose of Advil (ibuprofen) with one or two drinks is unlikely to cause serious harm in a healthy adult who does not do this regularly. The risk rises significantly when either substance is used frequently or in large amounts. The main danger is...
Xanax (alprazolam) and alcohol must not be combined. Both substances suppress the brain’s activity through the same receptor system, and together they can slow breathing to the point of stopping entirely. This is not a theoretical risk. The combination of...
Occasional light drinking is unlikely to cause serious harm for most people on metformin, but it is never entirely without risk. The three main dangers are lactic acidosis, low blood sugar, and worsening of diabetes control over time. Binge drinking is genuinely...
Alcohol and warfarin are a dangerous combination. Drinking while on warfarin can either raise your INR too high, increasing your risk of serious bleeding, or lower it too much, leaving you unprotected against blood clots. The direction of the risk depends on how much...
You should not drink alcohol while taking Zoloft (sertraline). Alcohol increases Zoloft’s side effects, reduces how well the medication treats depression and anxiety, and can worsen mood symptoms over time. There is no safe amount of alcohol to drink while on Zoloft,...
Mixing MDMA (ecstasy, molly) and alcohol is dangerous and the risks are more specific than most guides explain. MDMA reverses the serotonin, dopamine, and norepinephrine transporters simultaneously, flooding the brain with all three monoamines at once. Alcohol...
